Arterial Stiffness Is Increased in Young Women with Endometriosis
Anna TaniSatoshi YamamotoMasahiko MaegawaKotaro KunimiSumika MatsuiKaoruKeyamaTakeshi KatoHirokazu UemuraAkira KuwaharaToshiya MatsuzakiToshiyuki YasuiMasaharu KamadaTakeshi SoekiMasataka SataMinoru Irahara
Iseikai Hospital Japan
摘要：Endometriosis is a chronic gynecological disorder that is accompanied by inflammation and oxidative stress.Atherosclerosis has a long subclinical progression in arteries of children and young adults’ decades before overt clinical manifestations of the disease.In this study,we determined arterial stiffness by measuring brachial-ankle pulse wave velocity（baPWV） in women with endometriosis to assess the presence of subclinical atherosclerosis.We also measured markers of inflammation and oxidative stress in women with endometriosis.BaPWV in women with endometriosis aged over 30 years was significantly higher than that in women without endometriosis aged over 30 years（p＜0.05）,but not in women aged less than 30.Serum high-sensitivity（hs） CRP level in women with endometriosis was significantly higher than that in controls（p＜0.05）.Young women with endometriosis show significantly increased arterial stiffness,suggesting that women with endometriosis need to be cautious of the future onset of atherosclerosis.
BIT’s 5th International Congress of Gynaecology and Obstetrics-2017
Prague, Czech Republic