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Envenoming by Viridovipera Stejnegeri Snake:A Patient with Liver Cirrhosis Presenting Disruption of Hemostatic Balance

Chih-Ying ChienShu-Chen LiaoChien-Hung LiaoTing-Shuo HuangYu-Hsien Chen

Chang Gung Memorial Hospital

摘要:Background:In most cases of envenoming by the green habu Viridovipera stejnegeri in Taiwan coagulopathy is not observed.Case presentation:However,we describe a rare case of a patient with liver cirrhosis who developed venom-induced consvimptive coagulopathy after V.stejnegeri bite.Laboratory investigation revealed the following:prothrombin time>100 s(international normalized ratio>10),activated partial thromboplastin time>100 s,fibrinogen<50 mg/dL,and fibrin degradation product>80 μg/mL.The patient recovered after administration of bivalent hemorrhagic antivenom,vitamin K,fresh frozen plasma and cryoprecipitate.He didn’t have coagulopathy before this episode.Conclusion:The liver,directly involved in the acute phase reaction,is the main responsible for neutralization of animal toxins.Any patient with history of liver cirrhosis bitten by a venomous snake,even those whose venoms present low risk of coagulopathy,should be very carefully monitored for venom-induced consumptive coagulopathy(VICC),since the hemostatic balance may be disrupted.
会议名称:

2017第八届国际基因产业大会

会议时间:

2017-11-13

会议地点:

中国澳门

  • 专辑:

    医药卫生科技

  • 专题:

    消化系统疾病

  • 分类号:

    R575.2

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