文献知网节
  • 记笔记
摘要:Background and Aims:Prevalence of allergic diseases has dramatically increased over the recent decades,especially in children.Children living in urban area have a higher risk to allergic diseases than those living in rural area,and most studies implied the environmental exposure such as indoor and outdoor air pollutions as the main logical mechanism.This study aims to investigate whether housing with different patterns of driveway was associated with the development of allergic sensitization and allergic symptoms in childhood.Methods:A birth cohort was recruited in southern Taiwan.We enrolled 1124 infants with information of residential architecture from the 18month questionnaire.The questionnaire information of allergic diseases from both parents,and infants at 6-month (N=967) and 18-month (N=1124) and 36 months (N=924) were collected.The sensitization of common allergens and total IgE levels were measured by Phadia CAP system at the age of 18-month (N=713) and 36-month (N=652).We divided the driveway patterns of the housing into 3 groups including no driveway,2-lane driveway and 4-lane driveway.We compared the outcomes of allergic symptoms and allergic sensitization among children living in different driveway patterns of the housing at age of 6,18 and 36 months.Results:Children living in housings without a driveway had a higher risk to develop eczema (p=0.001),sneezing (p=0.049) at age of 6 and 18 months,and frequent cough or bronchiolitis (p<0.001) at age of 18 months than those living in the housing with 2-lane or 4-lane driveway.Children living in the housing without driveway also had higher total IgE levels and allergic sensitization to food allergen or aeroallergen at age of 6 and 18 months.The fact that both mothers and children living in a housing without driveway had significantly higher total IgE levels and allergic sensitization implies that people living in a housing without driveway are prone to the development of allergic sensitization and IgE production.Conclusion:Infants living in a housing without driveway had a higher risk to have allergy sensitization and to develop eczema and allergic respiratory symptoms than those living in the housing with 2-lane or 4-lane driveway.The housing building without driveway may have different constructing materials and may be much more enclosed which may contribute to low home ventilation and recycling of indoor pollutants and allergens for early development of allergic symptoms and allergic sensitization.
会议名称:

2012 International Conference on Environmental,Biomedical and Biotechnology

会议时间:

2012-08-04

会议地点:

Dubai, UAE

  • 专辑:

    医药卫生科技

  • 专题:

    儿科学

  • 分类号:

    R725.9

  • 手机阅读
    即刻使用手机阅读
    第一步

    扫描二维码下载

    "移动知网-全球学术快报"客户端

    第二步

    打开“全球学术快报”

    点击首页左上角的扫描图标

    第三步

    扫描二维码

    手机同步阅读本篇文献

  • CAJ下载
  • PDF下载

下载手机APP用APP扫此码同步阅读该篇文章

下载:4 页码:66-70 页数:5 大小:513k

引文网络
  • 参考文献
  • 引证文献
  • 共引文献
  • 同被引文献
  • 二级参考文献
  • 二级引证文献
  • 批量下载
相关推荐
  • 相似文献
  • 读者推荐
  • 相关基金文献
  • 相关法规
  • 关联作者
  • 相关视频