文献知网节
  • 记笔记

Paternal body mass index before conception associated with offspring’s birth weight in Chinese population: a prospective study

Xu,RenyingZhao,WeixiuTan,TaoLi,HaojieWan,YanpingGao,Xiang

Department of Clinical Nutrition,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong UniversityDepartment of Obstetrics,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong UniversityDepartment of Nutritional Sciences,The Pennsylvania State University,University Park

摘要:Objective Animal studies have shown that parental epigenetic information of nutrition and behavior might be inherited by subsequent generation. However, relevant human evidence has been limited to date. We thus performed a longitudinal study to evaluate the relationship between paternal preconception body weight and their offspring’s birth weight. Methods The current analysis included 1,810 Chinese mother-father-baby trios. Information on paternal and maternal preconception body weight and height was collected via a self-reported question at the first prenatal check-up and classified into three groups: normal, overweight, and obese according to the Working Group of Obesity in China(WGOC) criteria for adults. Information on birth weight was collected by review of medical records. The relationship between paternal preconception body weight and his children’s birth weight was examined by generalized linear model, adjusting for maternal demographic data, preconception BMI, and gestational weight gain, and other potential confounders. Results Higher paternal preconception body weight was associated with greater offspring’s birth weight(p trend=0.02). Per standard deviation(SD) increment of paternal BMI was associated with additional 29.6 g of birth weight [95% confident interval(CI): 5.7, 53.5 g]. In subgroup analyses, the association between paternal body weight and offspring’s birthweight was more pronounced in male neonates, and neonates with overweight mothers and with mothers who gained excessive gestational, relative to their counterparts(all p interaction<0.05). Conclusions Greater paternal preconception body weight was associated with greater birth weight of their offspring.
会议名称:

营养研究与临床实践——第十四届全国营养科学大会暨第十一届亚太临床营养大会、第二届全球华人营养科学家大会

会议时间:

2019-09-20

会议地点:

中国江苏南京

  • 专辑:

    医药卫生科技

  • 专题:

    预防医学与卫生学

  • DOI:

    10.26914/c.cnkihy.2019.011275

  • 分类号:

    R153.1

  • 手机阅读
    即刻使用手机阅读
    第一步

    扫描二维码下载

    "移动知网-全球学术快报"客户端

    第二步

    打开“全球学术快报”

    点击首页左上角的扫描图标

    第三步

    扫描二维码

    手机同步阅读本篇文献

  • CAJ下载
  • PDF下载

下载手机APP用APP扫此码同步阅读该篇文章

下载:1 页码:879-880 页数:2 大小:622k

引文网络
  • 参考文献
  • 引证文献
  • 共引文献
  • 同被引文献
  • 二级参考文献
  • 二级引证文献
  • 批量下载
相关推荐
  • 相似文献
  • 读者推荐
  • 相关基金文献
  • 相关法规
  • 关联作者
  • 相关视频