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5-aminolaevulinic acid (ALA), enhances heme oxygenase (HO)-1 expression and attenuates tubulointerstitial fibrosis and renal apoptosis in chronic cyclosporine nephropathy

Chi L.Ping Z.Masayuki F.Yoshitaka I.Hidenori I.Kiwamu T.Motowo N.Tohru T.Jian Z.Xiao-Kang L.

Division of Transplantation Immunology, National Research Institute for Child Health and DevelopmentGuangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical SciencesDepartment of Geriatric Medicine and Nephrology, Osaka University Graduate School of MedicineSBI Pharmaceuticals Co., Ltd.

摘要:<正>Background: Cyclosporine-A(CsA) is an immunosuppressant indicated for various immunological diseases; however, it can induce chronic kidney injury. Oxidative stress and apoptosis play a crucial role in CsA-induced nephrotoxicity. The present study evaluated the protective effect of combining 5-
会议名称:

第十七届国际免疫学大会

会议时间:

2019-10-19

会议地点:

中国北京

  • 专辑:

    医药卫生

  • 专题:

    泌尿科学

  • DOI:

    10.26914/c.cnkihy.2019.009003

  • 分类号:

    R692

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