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Unique impairment of CD1c+ myeloid DC in primary human blood-stage P. falciparum infection

Jessica R LoughlandGabriela MinigoJulie G BurelPeta E TippingKim A PieraFiona H AmanteChristian R EngwerdaMichael F GoodDenise L DoolanNicholas M AnsteyJames S Mc CarthyTonia Woodberry

Menzies School of Health Research and Charles Darwin UniversityQIMR Berghofer Medical Research InstituteGriffith UniversityJames Cook UniversityRoyal Darwin Hospital

摘要:<正>Malaria caused by Plasmodium remains a major global health problem,with 3.2billion people estimated at risk of infection.Protective immunity to malaria is slow to develop,incomplete and short-lived.Impairment of dendritic cell(DC)function is one way Plasmodium falciparum evades host immune responses.In 59malaria-naive adult volunteers,peripheral DC were examined before and after intra-venous P.falciparum infection with 150 or 1,800 parasite infected red blood
会议名称:

The 14th International Symposium on Dendritic Cells

会议时间:

2016-10-14

会议地点:

中国上海

  • 专辑:

    医药卫生科技

  • 专题:

    感染性疾病及传染病

  • 分类号:

    R531.3

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