Dendritic cell subsets and their role in the induction and regulation of immune responses to Schistosoma mansoni
Alexander Phythian-Adams1Peter Cook1Sheila Brown1Angela Marley2Garet h-Rhys Jones1Lucy Jones1Lauren Webb1Rick Maizels2Andrew Mac Donald1
1. Manchester Collaborative Centre for Inflammation Research, University of Manchester2. Wellcome Trust Centre for Molecular Parasitology, Institute for Infection,Immunity and Inflammation, University of Glasgow
摘要：＜正＞Whilst dendritic cells are essential for Th2 initiation against Schistosoma mansoni,the relative contributions of conventional DC（c DC）subsets are still under intense scrutiny.Batf3 dependent c DCs（Batf3-c DCs）have been linked to Th1 induction,Th2suppression and cross-presentation,whilst Irf4 dependent c DCs（Irf4-c DCs）may play a role in Th2 induction against allergens and helminths,and bacterial Th17responses.We have used Batf3-/-or CD11cCre+/+Irf4fl/fl mice to confirm whether the absence of
会议名称：
The 14th International Symposium on Dendritic Cells
会议时间：
2016-10-14
会议地点：
中国上海
- 专辑：
医药卫生科技
- 专题：
基础医学
- 分类号：
R383.2
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