节点文献

Correlation Analysis of Drug Resistance and Resistant Genotypes of Pathogenic Klebsiella peneumoniae from Racoon Dog to Fluoroquinolones

免费订阅

【作者】 Zhao XiaocuiLiu ZhiqiangLuo JunfengYao WeipingFeng LingWu TongleiZhang ZhiqiangBai XueFu YanfangGao QingshanJia QinghuiShi Qiumei

【Author】 Zhao Xiaocui;Liu Zhiqiang;Luo Junfeng;Yao Weiping;Feng Ling;Wu Tonglei;Zhang Zhiqiang;Bai Xue;Fu Yanfang;Gao Qingshan;Jia Qinghui;Shi Qiumei;Changli Bureau of Agriculture,Forestry, Animal Husbandry and Aquatic Products;Qilu Shenghua Pharmaceutical Co., Ltd.;Liushouying Animal Epidemic Surveillance Station, Agriculture and Animal Husbandry Bureau of Funing District;Leting Animal Husbandry Bureau;Hebei Normal University of Science and Technology/Hebei Key Laboratory of Preventive Veterinary Medicine;Institute of Special Animal and Plant Sciences of CAAS;Hebei Animal Husbandry Station;Animal Epidemic Prevention Station of Luanzhou Town, Luanzhou Bureau of Animal Husbandry and Aquatic Products;

【通讯作者】 Jia Qinghui;Shi Qiumei;

【机构】 Changli Bureau of Agriculture,Forestry, Animal Husbandry and Aquatic ProductsQilu Shenghua Pharmaceutical Co., Ltd.Liushouying Animal Epidemic Surveillance Station, Agriculture and Animal Husbandry Bureau of Funing DistrictLeting Animal Husbandry BureauHebei Normal University of Science and Technology/Hebei Key Laboratory of Preventive Veterinary MedicineInstitute of Special Animal and Plant Sciences of CAASHebei Animal Husbandry StationAnimal Epidemic Prevention Station of Luanzhou Town, Luanzhou Bureau of Animal Husbandry and Aquatic Products

【摘要】 [Objective] The paper was to analyze the correlation between drug resistance and resistant genotypes of pathogenic Klebsiella peneumoniae from racoon dog to fluoroquinolones. [Method] The drug resistance and resistant genes of 24 strains of pathogenic K. peneumoniae from racoon dog to fluoroquinolones were detected by K-B drug susceptibility paper and PCR. [Result] Multiple drug-resistant strains were dominant among 24 strains of pathogenic K. peneumoniae, and the drug resistance to levofloxacin, enrofloxacin, ciprofloxacin and norfloxacin was 70.8%-79.2%; the strains resistant to 4, 3 and 2 antibiotics were 58.3%, 29.2% and 8.3%, respectively. The detection rates of drug-resistant genes TEM, gyrB, parC,parE, gyrA and SHV were 75%-100%, and the number of strains carrying 9, 8, 7, 6, 4 and 3 drug-resistant genes was 4.2%-41.7%. Comparison of drug-resistant genes and drug resistance showed that the coincidence rates of levofloxacin, enrofloxacin, ciprofloxacin and norfloxacin were 78.9%-100%. [Conclusion] There were certain correlation between drug resistance and resistant genotypes of 24 strains of pathogenic Klebsiella peneumo-niae to fluoroquinolones.

【基金】 Supported by Project of Hebei Department of Science and Technology(18246629G);Project of Shijiazhuang Science and Technology Bureau(171500953A);Project of Hebei Department of Education(ZD2017234)
【所属期刊栏目】 Animal Disease and Drug (2019年01期)
  • 【DOI】10.19578/j.cnki.ahfs.2019.01.011
  • 【分类号】S852.61
  • 【下载频次】7
节点文献中: 

本文链接的文献网络图示:

浏览历史:
下载历史: