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Effect of RADIX et RHIZOMA RHODIOLAE CRENULATAE on the Immunologic Function of Mice

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【Author】 LI Li1*,WANG Qiu-shui2,WANG Ya-dong1,CHEN Dong-fang1,ZHANG Yan1,WANG Hai-yu1 1.Henan Center for Disease Control and Prevention,Zhengzhou,Henan 450016,China;2.Leshan Central Blood Banks of Sichuan Province,Leshan,Sichuan 614000,China

【摘要】 [Object] To investigate the effect of RADIX et RHIZOMA RHODIOLAE CRENULATAE on the immunity of mice.[Method] 192 BALB/C mice were randomly divided into 4 groups,and each group was divided into 4 treatments,i.e.,low dose group,middle dose group,high dose group and control group,then they were given medicine(20 ml/kg·weight) for 30 d,the immune indexes were determined.[Result] The carbon clearance ability of mice in high dose group was heightened(P<0.05);the delayed-type hypersensitivity(DTH) induced by sheep red blood cell(SRBC)(P<0.05),the activity of NK cell(P<0.05),the synthesis of serum prothrombin(P<0.05)and antibody cell(P<0.05),the phagocytosis of peritoneal macrophage(P<0.05) were all improved in middle and high dose groups,while the immune organs-body weight ratio and the transformation ability of mice spleen lymphocytes induced by ConA in middle and high dose groups were not promoted significantly.[Conclusion] RADIX et RHIZOMA RHODIOLAE CRENULATAE is endowed with the function of enhancing the immunity of mice,and this case would provide experimental experience for the development of valuable health food.

  • 【分类号】R285.5
  • 【下载频次】17
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