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Studies on Microbial Transformation of Tibetan Capillaris

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【Author】 WANG Hong1*,JIAO Ying-chun2,YU Mei3 1.College of Chemical Engineering,Qinghai University,Xining,Qinghai 810016,China;2.College of Life Science,Qinghai University,Xining,Qinghai 810016,China;3.Qinghai Plateau Pharmaceutical Co.,Ltd.,Xining,Qinghai 810007,China

【摘要】 [Objective] To explore transformation of neomangiferin into mangiferin under controlled conditions in vitro,so as to increase the content of mangiferin.[Method] Using Tibetan capillaries(Swertia przewalskii Pissjauk) as tested materials,microorganism fermentation was adopted to realize the transformation of neomangiferin into mangiferin.An efficient strain-screening model was established for selecting strains that could secret specific β-glucosidase by combing category of glycosidic bond with strain-screening technique.Furthermore,these screened strains were isolated,purified and identified.[Result] The upgrade rate of mangiferin content was 0.21% by measuring its content before and after fermentation.[Conclusion] This study was beneficial to reasonable development of mangiferin resource from Tibetan capillaris,which would provide pharmacological and pharmacy evidences for its clinical application.

  • 【分类号】TQ461
  • 【下载频次】34
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