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Extraction Technology of Total Alkaloids from RADIX ACONITI LATERALIS PRAEPARATA

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【Author】 LIU Zhuo,YAN Xing,XU Chun-xia,YUAN Xiao-hong School of Life Science and Engineering,Southwest University of Science and Technology,Mianyang,Sichuan 621000,China

【摘要】 [Objective] To determine the optimal extraction technology of total alkaloids from RADIX ACONITI LATERALIS PRAEPARATA.[Method] With dry extracts rate,and the purity and extraction rate of total alkaloids as the indices,effects of extraction solvent,extraction method,extraction temperature,extraction time,grind degree,solid-liquid ratio and extraction times on the extraction rate of total alkaloids were studied.And the optimal extraction technology was selected.[Conclusion] The optimal extraction technology was as follows:RADIX ACONITI LATERALIS PRAEPARATA crude powder was added into anhydrous ethanol with the ratio of 1:10(g/ml)under 15 ℃.After cold leaching for 3 times with each time for 1 d,the dry extracts rate,extraction rate of total alkaloids,and purity of total alkaloids were 3.15%,0.64% and 20.32%,respectively.[Conclusion] This method was efficient,low toxic,economical,convenient and can be used for industrial production.

【基金】 Supported by the Sichuan Provincial Support Program for Science and Technology Development(2008SZ0082)
  • 【分类号】R284.1
  • 【下载频次】31
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