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Research on the Period of Validity of RADIX ET RHIZOMA RHEI

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【作者】 Lei YANGQing ZHUZhiguo ZHANGChen CAO

【Author】 Lei YANG1*, Qing ZHU2, Zhiguo ZHANG1, Chen CAO1 1. The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Changsha, Hunan 410007, China; 2. Hunan Provincial Tumor Hospital, Changsha, Hunan 410013, China

【机构】 The First Affiliated Hospital of Hunan University of Traditional Chinese MedicineHunan Provincial Tumor Hospital

【摘要】 [Objective] To study the period of validity of traditional Chinese medicine RADIX ET RHIZOMA RHEI. [Method] RADIX ET RHIZOMA RHEI which were easily oxidized were selected. Based on classic constant temperature experiment, contents of rhein, archen, physcion and aloe-emodin were detected by HPLC. The change law of the effective components contents in RADIX ET RHIZOMA RHEI was deduced. [Result] Changes of rhein, archen, physcion and aloe-emodin contents followed the first-order reaction law. Under the storage condition of 20 ℃, the change rate constant of RADIX ET RHIZOMA RHEI was k=1.585×10-5; and the period of validity of this batch of RADIX ET RHIZOMA RHEI was 687 d. [Conclusion] It was feasible to forecast the validity period of RADIX ET RHIZOMA RHEI by classic constant temperature experiment, and the results were reliable.

【基金】 Supported by the Natural Science Foundation Program of Hunan Province( 10JJ5018)
  • 【分类号】TQ461
  • 【下载频次】18
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