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Advances in Pharmacological Activity of Febrifugine and Its Derivatives

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【作者】 Zhiting GUOJianping LIANGRuofeng SHANGWenzhu GUOYu LIU

【Author】 Zhiting GUO;Jianping LIANG;Ruofeng SHANG;Wenzhu GUO;Yu LIU;Key Laboratory of Veterinary Pharmaceutics Discovery,Ministry of Agriculture/Key Laboratory of New Animal Drug Project,Gansu Province,Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS;

【机构】 Key Laboratory of Veterinary Pharmaceutics Discovery,Ministry of Agriculture/Key Laboratory of New Animal Drug Project,Gansu Province,Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS,Lanzhou,Gansu 730050,ChinaKey Laboratory of Veterinary Pharmaceutics Discovery,Ministry of Agriculture/Key Laboratory of New Animal Drug Project,Gansu Province,Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS

【摘要】 The herbal Dichroa febrifuga Lour is the dried roots of Saxifragaceae plant species Dichroa febrifuga Lour that are endowed with the efficacies of inducing vomiting,insecticide,anti-malaria and relieving heat.It has been broadly applied for treating malaria in folk.We reviewed the advances in pharmacological activity of effective component febrifugine in Dichroa febrifuga Lour and its derivatives,and found that Dichroa febrifuga Lour has been documented effective in antitumor,anti-coccidium,anti-scar,anti-malaria,and the treatment of diabetes mellitus and osteoporosis as well.On the basis of this,we proposed to develop safe and efficient derivatives continuously by structural modification and perform immune study and their antitumor activity.

【基金】 Supported by Central Public-interest Scientific Institution Basal ResearchFund(No.1610322011004)
  • 【分类号】S853.7
  • 【下载频次】20
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