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Anti-inflammatory Effects of the Stems and Leaves of Platycodon randiflorum on Animal Models of Acute Inflammation

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【作者】 Lilan OUXin YUYe ZHUChun ZHANG

【Author】 Lilan OU;Xin YU;Ye ZHU;Chun ZHANG;Department of Pharmacy,Luzhou Medical College;

【机构】 Department of Pharmacy,Luzhou Medical College

【摘要】 [Objective]To study anti-inflammatory effects of water extract of the stems and leaves of Platycodon grandiflorum.[Methods]Observed anti-inflammatory effects of water extract of the stems and leaves of Platycodon grandiflorum using 4 kinds of animal models of acute inflammation which were consisted of rats’footpad swelling induced by egg white,ear swelling caused by xylene in mice,celiac capillary permeation in mice induced by 1%glacial acetic acid and the analgesia experiments of hot plate method.[Results]Water extract of the stems and leaves of Platycodon grandiflorum had a certain degree inhibition effect on ear swelling caused by xylene in mice,rats’footpad swelling induced by egg white and celiac capillary permeation in mice induced by acute inflammation.Compared with model group,low-dosage and highdosage groups of water extract of the stems and leaves of Platycodon grandiflorum were of significant differences(P<0.05 or P<0.01).[Conclusions]Water extract of the stems and leaves of Platycodon grandiflorum had strong anti-inflammatory effects.

  • 【分类号】S567.239
  • 【下载频次】11
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