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Experimental Study on the Antitussive,Apophlegmatic and Antiasthmatic Effect of Extract of Jianhua

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【作者】 Shujie FUXingzhen HUANGLingling WUFengming LONGXiuzhi WEIWeizhe JIANG

【Author】 Shujie FU;Xingzhen HUANG;Lingling WU;Fengming LONG;Xiuzhi WEI;Weizhe JIANG;Guangxi Medical University;The First People’s Hospital of Hechi;

【机构】 Guangxi Medical UniversityThe First People’s Hospital of Hechi

【摘要】 [Objective]To explore the antitussive,apophlegmatic and antiasthmatic effect of extract of Jianhua. [Methods]The antitussive, apophlegmatic and antiasthmatic effect of extract of Jianhua was studied by animal models. Control group,low-dosage group of extract of Jianhua,medium-dosage group of extract of Jianhua,high-dosage group of extract of Jianhua and positive medication group were included in the experiment. [Results] Compared with control group,low,medium and high-dosage of aqueous extract and alcohol extract of Jianhua could significantly inhibit cough induced by stronger ammonia water( P < 0. 05,P < 0. 01); medium and high-dosage of aqueous extract and alcohol extract of Jianhua could significantly increase phenol red excretion in the respiratory tract of mice( P < 0. 05,P < 0. 01); high-dosage of aqueous extract and alcohol extract of Jianhua could significantly prolong the incubation of asthma in guinea pigs induced by citric acid( P < 0. 05). [Conclusions]The extract of Jianhua had significant effect of relieving a cough,eliminating phlegm and relieving asthma.

【基金】 Nature and Science Fund of Guangxi(Guangxi Nature and Science 0991264);Project of Platform of Sci-tech Innovation Established by Education Department and Enterprise in Guangxi(Guangxi Educational and Sci-entific Research[2011]9);Project of Platform of Sci-tech Innovation Established by Education Department and Enterprise in Guangxi(Guangxi Educational and Scientific Research[2013]8-3)
【所属期刊栏目】 Pharmacological and Toxicological Analyses (2014年02期)
  • 【分类号】S567.239
  • 【被引频次】4
  • 【下载频次】12
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