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The Safety of Shampoo with Compound Zaofan Function

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【作者】 Xiangyu HUYan LIULiping YAOChunyan YANGWenxin YANG

【Author】 Xiangyu HU;Yan LIU;Liping YAO;Chunyan YANG;Wenxin YANG;TCM Hospital Affiliated to Luzhou Medical College;

【机构】 TCM Hospital Affiliated to Luzhou Medical College

【摘要】 [Objective] To discuss the safety of shampoo with compound Zaofan function to the skins of laboratory animals. [Methods]Kunming mice was used for skin acute toxicity test; domestic healthy rabbits were used for skin irritation test; and white guinea pigs were used for skin sensitivity test. Cell genetic toxicity of Shampoo with compound Zaofan function in the body was detected by lymphocyte micronucleus test on Kunming mice. [Results]After using the shampoo with compound Zaofan function,mice showed no symptom of acute toxicity. In skin irritation test,shampoo with compound Zaofan function had relatively weak stimulation to skin; and the degree was no irrigation. In skin sensitivity test,shampoo with compound Zaofan function had low incidence of sensitization and poor sensitization. In micronucleus test of lymphocyte,shampoo with compound Zaofan function had small effects on the teratogenicity / mutagenesis. [Conclusions]Shampoo with compound Zaofan function was safe and reliable for external use,and was worthy of clinical promotion.

【基金】 Supported by the Joint Research Project of Provincial Science&Technology Bureau of Sichuan Province-The People’s Government of Luzhou City-Luzhou Medical College(2014SZ0186);the Joint Key Project of Luzhou Medical College-TCM Hospital Affiliated to Luzhou Medical College([2013]12)
【所属期刊栏目】 Others (2015年Z1期)
  • 【分类号】R114
  • 【下载频次】40
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