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Effects of Boiling on Paeoniflorin Content in RADIX PAEONIAE ALBA

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【作者】 Xuegang ZHOU

【Author】 Xuegang ZHOU;College of Pharmacy,Harbin Medical University Daqing Campus;

【机构】 College of Pharmacy,Harbin Medical University Daqing Campus

【摘要】 [Objective] To preliminarily investigate the effects of boiling temperature and time on paeoniflorin content in RADIX PAEONIAE ALBA. [Methods] With paeoniflorin content in RADIX PAEONIAE ALBA as the evaluation index,high-performance liquid chromatography was adopted. Paeoniflorin contents in different underground parts by different processing methods were detected. Lichro CARTRP-C18( 4 mm ×250 mm,5 μm) was adopted; mobile phase was acetonitrile- 0. 1% phosphoric acid solution( 14∶ 86); flow rate was 1 m L / min; detection wavelength was 230 nm; column temperature was 30 ℃; and injection volume was 10 μL. [Results] Boiling temperature and time had relatively great impacts on paeoniflorin content. After RADIX PAEONIAE ALBA was boiled at 85 ℃ for 15 min,paeoniflorin contents all enhanced. Paeoniflorin contents of underground parts were in the order of rhizomes > fibrous roots > principal roots. [Conclusions]Complete and systematic research was needed on the chemical components and pharmacodynamics of both RADIX PAEONIAE ALBA and RADIX PAEONIAE RUBRA; only one index of paeoniflorin content was not enough. Fingerprint should be introduced into research; whether peeling was needed should be explicited.

【基金】 Supported by the National Science and Technology Support Program(2006BAI06A12-07);the Scientific Research Project of Provincial Department of Public Health of Heilongjiang(2012-784)
【所属期刊栏目】 Processing of Traditional Chinese Medicine and Quality Control (2015年Z4期)
  • 【分类号】R284
  • 【下载频次】28
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