节点文献

Effect of Shenfu Injection on Serum C-reactive Protein,Calcitonin and TNF-α in Patients with Septic Shock

免费订阅

【作者】 Siwei CHENDan ZHANGZhuo ZHANGFang WANG

【Author】 Siwei CHEN;Dan ZHANG;Zhuo ZHANG;Fang WANG;College of Pharmacy,Southwest Medical University;

【机构】 College of Pharmacy,Southwest Medical University

【摘要】 [Objectives] To explore the influence of Shenfu injection on serum C-reactive protein,blood calcium and TNF-α in the patients with septic shock. [Methods]According to admission order,78 patients with septic shock were randomly divided into control and experimental groups. Control group was treated by isopropyl epinephrine,and experimental group was treated by Shenfu injection on the basis of the control group. [Results] The total effective rate was 95. 00% for the experimental group,obviously higher than that of control group( 78. 95%)with significant difference( P < 0. 05). After 3-d treatment,the experimental group’s serum CRP and PCT levels were( 5. 83 ± 2. 51) mg / L and( 0. 97 ± 1. 12) μg / L,respectively,lower than the control group’s PCT and CRP levels of( 10. 31 ± 2. 15) mg / L and( 4. 82 ± 1. 10)μg / L,with significant difference( P < 0. 05); the experimental group’s serum TNF-α level was( 80. 83 ± 22. 51) ng / L,significantly lower than the control group’s TNF-α level of( 184. 31 ± 28. 37) ng / L,with significant difference( P < 0. 05). [Conclusions] The Shenfu injection had a good therapeutic effect on patients with septic shock,and it could improve the level of CRP,PCT and TNF-α,so it could be promoted in clinic practice.

【所属期刊栏目】 Pharmacological and Toxicological Analyses (2016年Z6期)
  • 【分类号】R459.7
  • 【下载频次】7
节点文献中: 

本文链接的文献网络图示:

浏览历史:
下载历史: