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A Study on the Chemical Constituents of Pilea sinofasciata C. J.Chen

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【作者】 Yan HUANGXu WUJianwen WENMingsheng CHENKaijia HEBuming LIU

【Author】 Yan HUANG;Xu WU;Jianwen WEN;Mingsheng CHEN;Kaijia HE;Buming LIU;Guangxi Institute of Traditional Medical and Pharmaceutical Sciences;Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards;

【机构】 Guangxi Institute of Traditional Medical and Pharmaceutical SciencesGuangxi Key Laboratory of Traditional Chinese Medicine Quality Standards

【摘要】 [Objectives] To study the chemical constituents of Pilea sinofasciata C. J. Chen. [Methods] Column chromatography,such as silica gel,Sephadex LH-20 and preparative HPLC were used to isolate and purify the compounds. Spectroscopic methods like MS,1H NMR and13C NMR and physical constants were used to elucidate their structure. [Results]Ninteen compounds were isolated from 95% ethanol extracts of Pilea sinofasciata C. J. Chen,including α-tocopherol(1),stigmasterol(2),epihernandulcin(3),hernandulcin(4),benzoic acid(5),ethyl linolenate(6),ethyl hexadecanoate(7),α-amyrin(8),palmitic acid(9),behenic acid(10),adenosine(11),indole-3-carboxylic acid(12),protocatechuate(13),gallic acid(14),betulinic acid(15),oleanolic acid(16),potassium nitrate(17),diosmetin7-O-β-D-glucopyranoside( 18),3-O-β-D-xylopyranosyl(1→2)-β-D-glucopyranosyl-28-O-β-D-glucopyranosyl oleanolic acid(19). [Conclusions] All of the compounds were isolated from the plant for the first time.

【基金】 Supported by Innovative Common Key Technology Research and Demonstration Project on Zhuang Medicine(Gui Ke Zhong 1355001-4,14124002-11);Guangxi Natural Science Foundation(2014GXNSFBA118142);Independent Research Project of Guangxi Key Laboratory of Traditional Chinese Medicine Quality Standards(Gui Zhong Zhong Zi 201408);Open Research Project of Guangxi Key laboratory of Chinese Medicine Efficacy Research(14-045-12-K3)
【所属期刊栏目】 Chemical Composition of Natural Medicine (2017年03期)
  • 【分类号】R284
  • 【下载频次】31
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