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Preparation Process of Liposome of Polysaccharides of Dicliptera chinensis

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【作者】 Riming WEIKefeng ZHANG

【Author】 Riming WEI;Kefeng ZHANG;Guilin Medical University;

【机构】 Guilin Medical University

【摘要】 [Objectives] The research aimed to study preparation process of liposome of polysaccharides of Dicliptera chinensis( DCP) and investigate its quality.[Methods] Thin film ultrasonic technology and uniform design were used to prepare DCP liposome,and the process was optimized. [Results] DCP liposome obtained by the optimized process had below parameters: entrapment efficiency( 54. 79 ± 1. 30) %,average drug loading rate( 5. 48 ± 0. 12) %,average particle size( 354. 63 ± 7. 04) nm,Zeta potential(-22. 51 ± 1. 13) m V. [Conclusions]DCP liposome obtained by the optimized process had higher entrapment efficiency and drug loading rate.

【基金】 Supported by Traditional Chinese Medicine Science and Technology Special Item of Guangxi Health and Family Planning Commission(GZBZ16-15)
【所属期刊栏目】 Processing of Traditional Chinese Medicine and Quality Control (2017年06期)
  • 【DOI】10.19600/j.cnki.issn2152-3924.2017.06.011
  • 【分类号】R283
  • 【下载频次】23
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