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Clinical Effect of Dendrobium officinale Kimura et Migo from Longhushan on Treatment of Type 2 Diabetes

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【作者】 Jun WUGuoxing WANGHuanghui ZHUANGZhitian MAOTianming LIWei LIHuiqin WU

【Author】 Jun WU;Guoxing WANG;Huanghui ZHUANG;Zhitian MAO;Tianming LI;Wei LI;Huiqin WU;Yujiang County Hospital of Traditional Chinese Medicine;Yingtan Tianyuan Xianhu Biotech Co.,Ltd;

【机构】 Yujiang County Hospital of Traditional Chinese MedicineYingtan Tianyuan Xianhu Biotech Co.,Ltd

【摘要】 [Objectives] To observe and compare the clinical effect and safety of Dendrobium officinale Kimura et Migo from Longhushan on treatment of type 2 diabetes. [Methods] 90 patients with type 2 diabetes were randomly divided into group A,group B and control group by randomized control method. Group A adopted D. officinale Kimura et Migo and metformin hydrochloride; group B adopted D. officinale Kimura et Migo; the control group adopted metformin hydrochloride. The fasting plasma glucose( FPG) of 3 groups was measured before the treatment and 2 weeks,4 weeks,6 weeks,8 weeks,10 weeks,and 12 weeks after the treatment,Hb A1 c was measured and diabetes symptom grade score was counted before the treatment and 12 weeks after treatment,observation indicators and clinical effect of 3 groups of patients were compared. [Results] The fasting plasma glucose level in group A was lower than that in other 2 groups,the difference was statistically significant( P < 0. 01),and there was no statistical significance in the difference between group B and the control group( P >0. 05); Hb A1 c of group A for 12 weeks after treatment was lower than that of other 2 groups,the difference was statistically significant( P < 0. 01),and there was no statistical significance in the difference between group B and the control group( P > 0. 05); the difference in diabetes symptom grade score of group A was greater than that in other 2 groups,the difference was statistically significant( P < 0. 01),and there was no statistical significance in the difference between group B and the control group( P > 0. 05). [Conclusions]D. officinale Kimura et Migo from Longhushan can effectively reduce the fasting plasma glucose level and Hb A1 c of type 2 diabetic patients and effectively improve the symptoms of patients; clinical application of D. officinale Kimura et Migo has equivalent effect with metformin hydrochloride,and combination of D. officinale Kimura et Migo with metformin hydrochloride has better effect than single use.

【所属期刊栏目】 Clinical Application (2017年06期)
  • 【DOI】10.19600/j.cnki.issn2152-3924.2017.06.016
  • 【分类号】R259
  • 【下载频次】24
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