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Systematic Review and Meta-analysis of Efficacy of Banxia Xiexin Decoction for Treatment of Bile Reflux Gastritis

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【作者】 Ningning ZHAOBing WEIShiying TANG

【Author】 Ningning ZHAO;Bing WEI;Shiying TANG;Department of Traditional Chinese Medicine, Chengde Medical University/Hebei Provincial Key Laboratory of Research and Development of Traditional Chinese Medicine, Chengde Medical University;

【通讯作者】 Shiying TANG;

【机构】 Department of Traditional Chinese Medicine, Chengde Medical University/Hebei Provincial Key Laboratory of Research and Development of Traditional Chinese Medicine, Chengde Medical University

【摘要】 [Objectives] The purpose was to study the clinical efficacy and safety of Banxia Xiexin decoction in treating bile reflux gastritis(BRG). [Methods] Randomized controlled trial was adopted to conduct scientific and standardized assessment on the risk of bias in the included articles. With overall effect and epigastric pain relief as indices, meta-analysis was performed, and sensitivity and safety analysis was conducted on the included literature. [Results] A total of 13 articles were included, involving a total of 1 478 patients. The results of meta-analysis show that the efficacy of Banxia Xiexin decoction alone and Banxia Xiexin decoction-Western medicine combination is better than that of Western medicine alone. [Conclusions] Banxia Xiexin decoction is safe and effective in treating bile reflux gastritis. However, as the 13 articles included are all low in quality and there is a certain degree of publication bias, the objectivity of the results is affected to some extent.

【所属期刊栏目】 Review (2020年03期)
  • 【DOI】10.19600/j.cnki.issn2152-3924.2020.03.003
  • 【分类号】R259
  • 【下载频次】3
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