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Clinical Observation of Huatanjieyu Granule in the Treatment of Post-stroke Depression

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【作者】 Xi WANGChunqi AILizhu LIUDongyu XIAQin GONG

【Author】 Xi WANG;Chunqi AI;Lizhu LIU;Dongyu XIA;Qin GONG;Sleep Disorder Center of Shiyan Taihe Hospital (Affiliated Hospital of Hubei University of Medicine);Shiyan Traditional Chinese Medicine Hospital;Mental Health Center of Shiyan Taihe Hospital (Affiliated Hospital of Hubei University of Medicine);

【通讯作者】 Xi WANG;

【机构】 Sleep Disorder Center of Shiyan Taihe Hospital (Affiliated Hospital of Hubei University of Medicine)Shiyan Traditional Chinese Medicine HospitalMental Health Center of Shiyan Taihe Hospital (Affiliated Hospital of Hubei University of Medicine)

【摘要】 [Objectives] To observe the clinical effect of Huatanjieyu granule on patients with post-stroke depression. [Methods] Total 76 patients with confirmed post-stroke depression were randomly divided into two groups(treatment group and control group) according to the double-blind principle. The treatment group(38 cases) was treated with Huatanjieyu granule combined with escitalopram, and the control group(38 cases) was treated with escitalopram alone. The course of treatment was 6 weeks. Through clinical efficacy, Hamilton Depression Scale(HAMD) and Treatment Emergent Symptom Scale(TESS) scores were compared, and blood, liver function, renal function and electrocardiogram were examined. [Results] The scores of HAMD and TESS in patients with post-stroke depression were significantly decreased by Huatanjieyu granule, and there were no obvious side effects. The total effective rate was 92.1% in the treatment group and 76.3% in the control group. There was significant difference between the two groups(P<0.01). [Conclusions] Huatanjieyu granule was effective in the treatment of post-stroke depression with little side effects and was easy to be accepted by patients.

【基金】 Supported by the Hospital-level Project of Shiyan Taihe Hospital in 2018(2018JJXM092);Shiyan Science and Technology Research and Development Project in 2018(18Y17)
【所属期刊栏目】 Clinical Application (2020年03期)
  • 【DOI】10.19600/j.cnki.issn2152-3924.2020.03.023
  • 【分类号】R277.7
  • 【下载频次】5
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