节点文献

Definition of Planarian Mortality in an Acute Toxicity Test: A Case Study on Dugesia japonica Exposed to 1-Octyl-3-methylimidazolium Bromide

免费订阅

【作者】 Zhang HecaiLiu TongyiLiu YanfangZhang JieWang ZhigeChen Guangwen

【Author】 Zhang Hecai;Liu Tongyi;Liu Yanfang;Zhang Jie;Wang Zhige;Chen Guangwen;College of Life Sciences,Henan Normal University;

【机构】 College of Life Sciences,Henan Normal University

【摘要】 In order to define the mortality criteria of planarian objectively,a case study of Dugesia japonica exposed to 1-octyl-3-methylimidazolium bromide([C8mim]Br)was performed followed by a recovery culture.The results showed that defining planarian mortality in light of its body disintegration was appropriate.If the disintegrated tissue of a planarian was more than 1/4 of its body length,it would completely degenerate.However,a planarian would regenerate the lost tissue and return to normal after a few days’recovery culture if the disintegrated part was less than 1/4 of body length.Therefore,we propose to use body disintegration as the endpoint of planarian mortality,i.e.,1/4 body length degenerated is the critical threshold of mortality and survival of planarians when exposed to toxicants.This criterion could be adapted in the standardization of testing protocols and comparability of acute toxicity test or other toxicological research using planarian as the test animal.

【基金】 supported by the National Natural Science Foundation of China(31471965);the Natural Science Foundation of Henan P rovince(142300410457);the National Student Innovation Training P roject of Henan Normal University(201410476051)
【所属期刊栏目】 专论 (2016年06期)
  • 【分类号】X171.5
  • 【下载频次】19
节点文献中: 

本文链接的文献网络图示:

浏览历史:
下载历史: