文献知网节
  • 记笔记

Synthesis,Crystal Structure and Antitumor Activity of a New Zn(Ⅱ) Complex Based on N-Acetyl-L-phenylalanine and 1,10-Phenanthroline

台夕市王欣游海英

College of Chemistry and Chemical Engineering,Weifang UniversityDepartment of Chemistry,Qinghai Normal UniversityWeifang University of Science and Technology

摘要:A new Zn(Ⅱ) complex, [Zn(L)2(phen)(H2O)](1, HL = N-acetyl-L-phenylalanine, phen = 1,10-phenanthroline) has been synthesized and characterized by elemental analysis, IR and X-ray single-crystal diffraction analysis. The Zn(Ⅱ) complex belongs to monoclinic, space group P21 with a = 12.6749(13), b = 5.5965(6), c = 22.985(2) ?, β = 104.296(2)°, V = 1580.0(3) ?3, Z = 2, Mr = 676.02, Dc = 1.421 μg·m-3, μ = 0.833 mm-1, F(000) = 704, and the final R = 0.0460, wR = 0.0899 for 4422 observed reflections with I > 2σ(I). The molecules form a 1D chained structure by hydrogen bonds. The antitumor activities of Zn(Ⅱ) complex against human hepatoma SMMC-7721 cells, human lung adenocarcinoma A549 cells and human colon carcinoma WiDr cells have also been investigated.
  • DOI:

    10.14102/j.cnki.0254-5861.2011-0910

  • 专辑:

  • 专题:

  • 分类号:

    O641.4

  • 手机阅读
    即刻使用手机阅读
    第一步

    扫描二维码下载

    "移动知网-全球学术快报"客户端

    第二步

    打开“全球学术快报”

    点击首页左上角的扫描图标

    第三步

    扫描二维码

    手机同步阅读本篇文献

  • CAJ下载
  • PDF下载

下载手机APP用APP扫此码同步阅读该篇文章

下载:14 页码:586-590 页数:5 大小:200K

引文网络
  • 参考文献
  • 引证文献
  • 共引文献
  • 同被引文献
  • 二级参考文献
  • 二级引证文献
  • 批量下载
相关推荐
  • 相似文献
  • 读者推荐
  • 相关基金文献
  • 相关法规
  • 关联作者
  • 相关视频